What Is THC-O Vape Pen, and Is It Harmful?

A blue vape pen placed on the table.

THC-O is a synthetic cannabinoid derived from hemp using acetic anhydride. The abbreviation THC-O stands for tetrahydrocannabinol-O-acetate. Although it has an acetate group, this compound’s basic structure is similar to that of delta-9. However, this extra portion of the molecule means it’s more powerful than other THC forms. 

The compound has become more well-liked due to its potent intoxication level and its unregulated position. THC-O is five times more potent than delta-8 THC and three times more potent than delta-9 THC. A typical THC-O dose causes some euphoric effects, similar to those of delta-9 but without the psychedelic and hallucinogenic effects.

Unlike delta-8 and delta-9 THCs extracted from the cannabis plant, THC-O-acetate doesn’t occur naturally. As a result, it can only be produced in laboratories by taking delta-9 THC and adding acetic anhydride, which causes delta-9 THC to bind to acetate to create THC-O. 

A THC-O vape pen consistently produces hits that are incredibly smooth. Additionally, consumers believe it has a euphoric and calming effect, which is great for unwinding after a hard day.

Is THC-O Legal?

Although THC-O is not legally prohibited, its legality is currently ambiguous. The 2018 Farm Bill authorized the cultivation of industrial hemp, which has a THC content below 0.3 percent, which is where THC-O originates.

What Are the Effects of Using THC-O?

THC interacts with endocannabinoid system receptors, which aids in reducing pain and regulating mood and other emotions. As a result, using this chemical may give you a high or euphoric feeling. The psychotropic substance found in cannabis is THC. THC-O acetate is also a prodrug, which means that it is not biologically active until it is absorbed by the body.

Each of us reacts to THC-O differently because we are all unique. Every THC-O user has, however, noted some universal effects. Euphoria, relaxation, talkativeness, pain alleviation, improved creativity, increased appetite, etc. are a few of these experiences. However, when taken in higher doses, there have been a few instances of unfavorable responses. These include feeling tense, scared, queasy, puzzled, and so on. Nonetheless, the THC-O vape pen is excellent if you want to unwind after a long day because of its calming and euphoric effects.

Moreover, a low THC-O dose induces a mildly euphoric high, the same as delta-8 THC. On the other hand, a high THC-O dose can leave you cognitively and physically incapacitated for some time. A study by the U.S Army also indicates that THC-O damaged dogs’ muscular coordination more than delta-9-THC.

THC-O effects take longer to show in your body, unlike delta-9. With oral consumption, delta-9 effects show within 20 to 30 minutes, while that of THC-O can take up to one hour or more. Similarly, when inhaled, the delta-8 THC effect is almost immediate, while with THC-O, it can take more than 20 minutes to show.

Is a THC-O Vape Pen Harmful?

First of all, THC-O is still relatively new on the market, therefore its immediate and long-term impacts on your body are not well understood. Second, THC-O quality varies from batch to batch due to insufficient quality control. Thirdly, since THC-O is manufactured in a lab, creating your own is dangerous. Make sure you thoroughly investigate your THC-O supplier to verify that you will receive a pure product free from chemical contamination.

To ensure that the THC-O vape pen is free from impurities, go for products that have undergone third-party lab testing. The manufacturer should also provide a certificate of analysis.

THC-O Dosage

THC-O should only be vaporized at a dosage of 0.5mg. 3mg is sufficient when taking it orally or through oil. Beyond this point, consumption can induce drunkenness and have psychedelic effects.

How to Use a THC-O Vape Cart

Vape carts like this https://purekana.com/products/thc-o-vape-pens-900mg/, are among the best methods to use THC-O because they work with all 510-threaded devices. You should set your temperature between 3.5 and 3.8 volts because the fluid is quite viscous. The THC-O Vape Pens are also easy to use. Just press the button three or five times, depending on the device, to switch it on and off. In addition to that, other devices are rechargeable. 


Compared to delta-9 THC, THC-O is synthetic and has triple the potency. As such, purchasing a high-quality THC-O product is crucial since you can be guaranteed of its safety. Different people respond differently to THC-O. A proper dosage would also aid in preventing psychedelic and hallucinogenic effects. Start out gently and move slowly when you are a newbie. Furthermore, consult a doctor before using THC-O if you have any pre-existing psychological conditions.

About Carson Derrow

My name is Carson Derrow I'm an entrepreneur, professional blogger, and marketer from Arkansas. I've been writing for startups and small businesses since 2012. I share the latest business news, tools, resources, and marketing tips to help startups and small businesses to grow their business.